Rapid Methadone Titration for Opioid Withdrawal Management

JAMA Internal Medicine 2026

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Authors: William C. Oles, Gregory T. Woods
DOI: 10.1001/jamainternmed.2026.0354
Cited by: 1
References: 5

Abstract

This Teachable Moment describes how traditional titration protocols for patients with fentanyl use disorder may be inadequate for patients with frequent, high-dose, or high-potency opioid use.

Fields of Study & Subjects

Pain Management and Opioid Use Opioid Use Disorder Treatment Forensic Toxicology and Drug Analysis

Publication details

Journal / source
JAMA Internal Medicine
Publisher
American Medical Association (AMA)
Volume
186
Issue
6
Pages
756–756
Publication date
6 April 2026
Language
EN