Pancreatic Cystic Neoplasm Risk Among Individuals With Diabetes

Importance: With advancements in imaging technology and more frequent health evaluations, the incidence and prevalence of pancreatic cysts have gradually increased. Certain types of pancreatic cystic neoplasms are precancerous lesions associated with an increased risk of pancreatic cancer. Hence, identifying risk factors and preventing their occurrence are crucial. Nonetheless, population-based research on modifiable risk factors remains lacking. Objective: To investigate the association of diabetes and related factors with risk of developing pancreatic cysts. Design, Setting, and Participants: This population-based cohort study included adults (aged ≥20 years) who underwent health examinations in 2009 through medical institutions designated by the Korean National Health Insurance Service. Participants were followed up until December 31, 2020. Data were analyzed from March 23, 2023, to February 8, 2024. Exposure: All participants were categorized according to diabetes status as having normoglycemia, impaired fasting glucose, shorter diabetes duration (