Comorbid Depression in Atopic Dermatitis—The Itch-to-Brain Circuitry Theory

JAMA Psychiatry 2026

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Authors: Ian McConnell, John M. Davis, Santosh Kumar Mishra
DOI: 10.1001/jamapsychiatry.2026.0029
Cited by: 1
References: 10

Abstract

This Viewpoint explores the itch-to-brain circuitry theory, a model to better understand atopic dermatitis–generated comorbid depression mechanisms, which could help improve the care of individuals with these comorbid conditions.

Fields of Study & Subjects

Dermatology and Skin Diseases Psoriasis: Treatment and Pathogenesis Stress Responses and Cortisol

Publication details

Journal / source
JAMA Psychiatry
Publisher
American Medical Association (AMA)
Volume
83
Issue
5
Pages
435–435
Publication date
4 March 2026
Language
EN