Clinical Trials for Children and Adolescents With Cancer in Latin America

Pediatric Blood & Cancer 2026

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Authors: Catrian Sotelo, Margit K. Mikkelsen, Oscar R Gonzalez-Ramella, Milena Villarroel C., Mackenzie Kelley, Michael Edwards, Ryan R. Lion, Hanna Ravi, Paola M. Friedrich, Carlos Rodriguez Galindo, Guillermo Luis Chantada, Daniel C. Moreira
DOI: 10.1002/1545-5017.70136
Cited by: 0
References: 13

Abstract

The improvement of childhood cancer outcomes has relied on clinical trials. The WHO's International Clinical Trials Registry Platform was searched for interventional clinical trials for children and adolescents with cancer in Latin America. Forty-seven trials were identified. Institutions were the primary sponsors for 38 (88.8%) trials, and 31 (65.9%) were conducted at a single site. Supportive care interventions (26, 55.3%) were more common than cancer-directed treatment trials. Thirteen (27.6%) trials had published results. Few trials were registered in Latin America. Strengthening research infrastructure and fostering collaborations are essential for equity in pediatric cancer research in the region.

Fields of Study & Subjects

Acute Lymphoblastic Leukemia research Advances in Oncology and Radiotherapy Statistical Methods in Clinical Trials

Publication details

Journal / source
Pediatric Blood & Cancer
Volume
73
Issue
4
Pages
e70136–e70136
Publication date
16 January 2026
Language
EN