Physiologically Adaptive Soft Millirobot for Atraumatic Endovascular Therapy

Advanced Functional Materials 2026 Open access

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Authors: Tuan‐Anh Le, Husnu Halid Alabay, Prabh G. Singh, Melissa Gioia Austin, Pamela A. Manco Urbina, Sanjay Misra, Hakan Ceylan
DOI: 10.1002/adfm.202531400
Cited by: 2
References: 59

Abstract

Atraumatic and localized drug delivery to the vascular endothelium remains a critical unmet need in interventional medicine, with major implications for arterial and venous disease management. Here, we present EndoBot, a soft, untethered millirobot designed to enable physiologically adaptive endoluminal interaction for atraumatic navigation and localized drug delivery under blood flow. EndoBot employs mechanically adaptive surface crawling that allows it to traverse non-uniform and curved vasculature while maintaining low radial contact pressures (

Fields of Study & Subjects

Micro and Nano Robotics Soft Robotics and Applications Advanced Materials and Mechanics

Publication details

Journal / source
Advanced Functional Materials
Publisher
Wiley
Volume
36
Issue
35
Publication date
4 February 2026
Language
EN