An Ultrapotent, Ultraeconomical, Antifreeze Polypeptide (Adv. Mater. 4/2026)

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Authors: Thomas J. McPartlon, Charles T. Osborne, Ke Wang, Rachel E. Detwiler, Konrad Meister, Jessica R. Kramer
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Abstract

Antifreeze Polypeptide Freezing damage is a challenge in biomedicine and foods. Extremophiles like polar fish have evolved antifreeze proteins that prevent damage to their tissues. In their Research Article (DOI: 10.1002/adma.202420504), Jessica R. Kramer and co-workers present ultra-economical protein mimetics that inhibit growth of large ice crystals and prevent freezing damage in sensitive enzymes, antibodies, and foods.

Fields of Study & Subjects

nanoparticles nucleation surface interactions Freezing and Crystallization Processes Protein Structure and Dynamics

Publication details

Journal / source
Advanced Materials
Volume
38
Issue
4
Publication date
1 January 2026
Language
EN