Mesenchymal Stem Cell‐Inspired Microneedle Platform for NIR‐responsive Immunomodulation and Accelerated Chronic Wound Healing (Adv. Mater. 11/2026)

Advanced Materials 2026 Open access

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Authors: Chan Ho Moon, Hee Gyeong Ko, Hyun‐Woo Lee, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Jong Hwa Seo, N. S. Lee, So Won Jeon, Yun‐A Kim, Jong‐Seo Yoon, Kyung‐Yup Cha
+10 more Min‐Ho Kang, Dongjin Lee, Soo‐Hong Lee, Gi Doo, Kisuk Yang, Donghyun Lim, Heemin Kang, Su Ryon Shin, Han Young Kim, Hyun‐Do Jung
DOI: 10.1002/adma.72363
Cited by: 1

Abstract

Mesenchymal Stem Cell-Inspired Microneedle In their Research Article (DOI: 10.1002/adma.202514081), Hyun-Do Jung, Han Young Kim and co-workers introduce a mesenchymal stem cell (MSC)–inspired microneedle that mimics adaptive MSC secretion. A dual-compartment design integrates photothermal MXene nanosheets and MSC-derived nanovesicle–DNA conjugates for near-infrared–triggered release, regulating inflammation, promoting angiogenesis, and accelerating tissue remodeling in chronic diabetic wounds. This biomimetic–nanomaterial platform enables immune-regenerative wound therapy.

Fields of Study & Subjects

Wound Healing and Treatments Graphene and Nanomaterials Applications Carbon and Quantum Dots Applications

Publication details

Journal / source
Advanced Materials
Publisher
Wiley
Volume
38
Issue
11
Publication date
1 February 2026
Language
EN