Electron Donor–Acceptor Mediated Hydrosulfonylation of Olefins From N ‐Hydroxymethylphthalimide Sulfones
Abstract
Sulfones are widely used sulfur‐VI motifs in pharmaceuticals. We report a hydrosulfonylation strategy that employs N ‐hydroxymethylphthalimide sulfones as versatile sulfinyl radical precursors. In the presence of tertiary amines, NHMP sulfones form electron donor–acceptor complexes that undergo light‐induced single‐electron transfer to generate sulfinyl radicals in the absence of a photocatalyst. The resulting radicals add efficiently to activated olefins, affording structurally diverse sulfones under mild conditions.
Fields of Study & Subjects
Sulfur-Based Synthesis Techniques
Radical Photochemical Reactions
Catalytic C–H Functionalization Methods
Publication details
- Journal / source
- Advanced Synthesis & Catalysis
- Publisher
- Wiley
- Volume
- 368
- Issue
- 12
- Publication date
- 15 June 2026
- Language
- EN