Visible‐Light‐Induced Cross‐Dehydrogenative Coupling of N ‐Sulfonyl Ketimines With Alkanes and Ethers

Advanced Synthesis & Catalysis 2026

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Authors: Hao Cheng, Zhangjie Zhou, Chao Shen, Pengfei Zhang
DOI: 10.1002/adsc.70628
Cited by: 6
References: 35

Abstract

A visible light‐induced cross‐dehydrogenative coupling (CDC) strategy has been developed for the direct CH alkylation of N ‐sulfonyl ketimines using readily available alkanes and ethers as alkyl sources. Employing 2‐chloroanthraquinone as an organic photocatalyst and atmospheric oxygen as a green terminal oxidant, the reaction proceeds efficiently under visible light irradiation at room temperature without the need for external metal catalysts, stoichiometric oxidants, or additives. This protocol enables the synthesis of a diverse range of 4‐alkylated sulfonyl ketimines with functional group compatibility. Mechanistic studies indicate that the reaction proceeds via a radical pathway involving a hydrogenatom transfer (HAT) process.

Fields of Study & Subjects

Radical Photochemical Reactions Catalytic C–H Functionalization Methods Sulfur-Based Synthesis Techniques

Publication details

Journal / source
Advanced Synthesis & Catalysis
Publisher
Wiley
Volume
368
Issue
14
Publication date
7 July 2026
Language
EN