Self‐Trapped Excitons in Carbon Quantum Dots with Large NIR‐II Photo‐Thermoelectric Catalysis Induce Pyroptosis for Cancer Therapy (Adv. Sci. 4/2026)

Advanced Science 2026 Open access

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Authors: Tesen Zhang, Qingcheng Wang, Quansheng Cheng, Han Wang, He Feng, Hui Zhang, Mengbo Lin, Feili Cai, Zheng Fang, Ruo Lan Wang, Gang Chen
DOI: 10.1002/advs.73394
Cited by: 2

Abstract

NIR-II Pyroptosis Agents This study develops carbon quantum dots with high-density self-trapped excitons that exhibit strong NIR-II absorption and exceptional photothermal conversion. Through photo-thermoelectric catalysis, they generate cytotoxic radicals, triggering pyroptosis. This approach not only ablates primary tumors but also activates systemic antitumor immunity, effectively creating an in situ cancer vaccine and offering a novel strategy for precision immuno-oncology. More details can be found in the Research Article by Gang Chen, Tesen Zhang, Ruo Wang, Zheng Fang, and co-workers (DOI: 10.1002/advs.202514249).

Fields of Study & Subjects

Carbon and Quantum Dots Applications Nanoplatforms for cancer theranostics Gold and Silver Nanoparticles Synthesis and Applications

Publication details

Journal / source
Advanced Science
Publisher
Wiley
Volume
13
Issue
4
Publication date
1 January 2026
Language
EN