Temporal Stretch‐Induced Nuclear Mechanosensing Coordinates Early Chromatin Accessibility and Genome Protection (Adv. Sci. 5/2026)

Advanced Science 2026 Open access

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Authors: Hye-Won Shim, Ji‐Young Yoon, Hwalim Lee, Shanika Karunasagara, Cheng Ji Li, Yongdae Shin, Sukbum Hong, Dong‐Joon Lee, Jung‐Hwan Lee, Kam W. Leong, Hae‐Won Kim
DOI: 10.1002/advs.73401
Cited by: 0

Abstract

Temporal Stretch-Induced Nuclear Mechanosensing Cells subjected to temporal mild stretching rapidly activate their nuclear mechanosensing machinery, leading to changes in nuclear mechanics and epigenetic states that upregulate genes involved in genome protection and cellular plasticity. More details can be found in the Research Article by Jung-Hwan Lee, Kam W. Leong, Hae-Won Kim, and co-workers (DOI: 10.1002/advs.202510554).

Fields of Study & Subjects

Cellular Mechanics and Interactions Nuclear Structure and Function Genomics and Chromatin Dynamics

Publication details

Journal / source
Advanced Science
Volume
13
Issue
5
Publication date
1 January 2026
Language
EN