Human Atlas of Tooth Decay Progression: Identification of Cellular Mechanisms Driving the Switch from Dental Pulp Repair Toward Irreversible Pulpitis (Adv. Sci. 8/2026)

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Authors: Hoang Thai Ha, Sofya Kosmynina, Amandine Verocq, Kerem Ozen, Ines Tekia, Hugo Bussy, Marie Ramirez, Dima Sabbah, Chloé Goemans, Valerie Vandenbempt, Esteban N. Gurzov, Sumeet Pal Singh
+1 more Nicolas Baeyens
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Abstract

Human Atlas of Tooth Decay Progression This cover presents a high-resolution volumetric image of the vasculature within a healthy human dental pulp. This 3D reconstruction reveals the remarkable complexity and beauty of the pulp's microvascular tree, captured through advanced clearing and imaging approaches. The result is an extraordinary visualization of the living architecture that supports tooth function. More details can be found in the Research Article by Hoang Thai Ha, Nicolas Baeyens, and co-workers (DOI: 10.1002/advs.202510096).

Fields of Study & Subjects

Endodontics and Root Canal Treatments Dental materials and restorations Oral microbiology and periodontitis research

Publication details

Journal / source
Advanced Science
Volume
13
Issue
8
Publication date
1 February 2026
Language
EN