Electrochemical C3‐Sulfonylation of Imidazo[1,2‐ a ]pyridines With Sulfonyl Hydrazides

Asian Journal of Organic Chemistry 2026

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Authors: Qing‐Miao Pu, Bing‐Yu Luo, Xue Ran, Xiao‐Dong Su, Ke‐Jin Jiao, Xiao‐Tong Gao
DOI: 10.1002/ajoc.70327
Cited by: 1
References: 60

Abstract

ABSTRACT Herein, a transition metal‐ and oxidant‐free electrochemical method for the direct C3–sulfonylation of imidazo[1,2‐ a ]pyridines using sulfonyl hydrazides as sulfonylation reagents has been developed. This methodology provides an efficient and practical protocol for the synthesis of 3‐(arylsulfonyl)imidazo[1,2‐ a ]pyridines, featuring mild reaction conditions, broad substrate scope and enhanced atom economy. Various imidazo[1,2‐ a ]pyridines and sulfonyl hydrazides could be selectively transformed into the corresponding C3–sulfonylated products in moderate to excellent yields.

Fields of Study & Subjects

Sulfur-Based Synthesis Techniques Radical Photochemical Reactions Catalytic C–H Functionalization Methods

Publication details

Journal / source
Asian Journal of Organic Chemistry
Publisher
Wiley
Volume
15
Issue
2
Publication date
1 February 2026
Language
EN