Mannose‐Modified Cationic Liposome‐Based mRNA Therapeutics for Improved Triple‐Negative Breast Cancer Immunotherapy
Abstract
Cancer Immunotherapy A mannose-modified cationic liposome (cLipo)-based mRNA therapeutic (cLipo-Man/mTEM8) was developed for triple-negative breast cancer (TNBC) immunotherapy. It targets dendritic cells to boost T cell responses and release cytokines, which leads to tumor suppression. More details can be found in the Research Article by Chanyuan Jin, Can Yang Zhang, and co-workers (DOI: 10.1002/anbr.202500226).
Fields of Study & Subjects
RNA Interference and Gene Delivery
Immunotherapy and Immune Responses
Nanoparticle-Based Drug Delivery
Publication details
- Journal / source
- Advanced NanoBiomed Research
- Volume
- 6
- Issue
- 3
- Publication date
- 1 March 2026
- Language
- EN