Mannose‐Modified Cationic Liposome‐Based mRNA Therapeutics for Improved Triple‐Negative Breast Cancer Immunotherapy

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Authors: Kexin Deng, Juping Sun, Junyu Liu, Youqi Zhang, Wanwan Liu, Xiaobin Li, Zhigang Wu, Juan Li, Jisong Zhang, Chanyuan Jin, Can Yang Zhang
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Abstract

Cancer Immunotherapy A mannose-modified cationic liposome (cLipo)-based mRNA therapeutic (cLipo-Man/mTEM8) was developed for triple-negative breast cancer (TNBC) immunotherapy. It targets dendritic cells to boost T cell responses and release cytokines, which leads to tumor suppression. More details can be found in the Research Article by Chanyuan Jin, Can Yang Zhang, and co-workers (DOI: 10.1002/anbr.202500226).

Fields of Study & Subjects

RNA Interference and Gene Delivery Immunotherapy and Immune Responses Nanoparticle-Based Drug Delivery

Publication details

Journal / source
Advanced NanoBiomed Research
Volume
6
Issue
3
Publication date
1 March 2026
Language
EN