Bioorthogonally Activatable Chemiluminescence for the N ‐Methyl‐ d ‐aspartate Receptors Intravital Imaging

Angewandte Chemie 2026

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Authors: Simiao Cheng, Mingyue Zhang, Jian Zhang, Xilei Xie, Yong Li, Xueyu Dou, Xiaoyun Jiao, Yujie Tang, Xu Wang, Bo Tang
DOI: 10.1002/ange.202523648
Cited by: 1
References: 30

Abstract

Abstract The signal attenuation caused by skull/vertebrae remains a challenge in central nervous system (CNS) receptor imaging. Chemiluminescence (CL), free from external excitation, offers unparalleled tissue penetration in optical imaging. However, existing 1,2‐dioxetane CL systems are shackled by two limitations: (i) short half‐lives (

Fields of Study & Subjects

bioluminescence and chemiluminescence research Click Chemistry and Applications Nanoplatforms for cancer theranostics

Publication details

Journal / source
Angewandte Chemie
Publisher
Wiley
Volume
138
Issue
9
Publication date
18 January 2026
Language
EN