Inside Back Cover: Molecular Cages as Probes in Indicator Displacement Assays: The Case of Scopolamine Detection (Angew. Chem. Int. Ed. 9/2026)
Abstract
A novel sensing strategy using molecular cages in an indicator displacement assay to detect scopolamine, a drug often implicated in drug-facilitated sexual assaults. The mechanism relies on the drug-induced transformation of non-emissive [Fluorescein2⊂Cage] into [Scopolamine⊂Catenane], releasing highly emissive free fluorescein. This turn-on response enables drug detection and quantification via fluorescence spectroscopy. More in the Research Article (e23575) by Ramón Martínez-Máñez, Vicente Martí-Centelles, and co-workers.
Fields of Study & Subjects
Supramolecular Chemistry and Complexes
Molecular Sensors and Ion Detection
Luminescence and Fluorescent Materials
Publication details
- Journal / source
- Angewandte Chemie International Edition
- Volume
- 65
- Issue
- 9
- Publication date
- 10 February 2026
- Language
- EN