Synthesis of 2,3‐Dihydroquinazolin‐4(1H)‐ones via Direct Cyclocondensation Reaction Using Chromium (III) Coordinated to 2‐[(2‐Amino‐ethylimino) methyl]‐6‐methoxyphenol Decorated Fe 3 O 4 @Silicapropyl as an Efficient and Magnetically Recoverable Nanocatalyst
Abstract
ABSTRACT Chromium (III) coordinated to 2‐[(2‐amino‐ethylimino) methyl]‐6‐methoxyphenol decorated Fe 3 O 4 @Silicapropyl Nps was synthesized and characterized by FT‐IR, FE‐SEM, TEM, XRD, VSM, TGA‐DTG, DLS, and EDX. Then, the application of this new nano catalyst for the Synthesis of 2,3‐dihydroquinazolin‐4(1H)‐ones via direct cyclocondensation reaction of various aldehydes and 2‐aminobenzamide was investigated. The procedure proceeded in high yields and short reaction times. Easy preparation of the catalyst, easy work‐up, and use of solvent‐free conditions are the main advantages of the protocol. The nanocatalyst can be reused for six reaction cycles with no notable decrease in catalytic efficiency.
Fields of Study & Subjects
Multicomponent Synthesis of Heterocycles
Quinazolinone synthesis and applications
Chemical Synthesis and Reactions
Publication details
- Journal / source
- Applied Organometallic Chemistry
- Volume
- 40
- Issue
- 4
- Publication date
- 25 February 2026
- Language
- EN