Click Chemistry by Mes‐Imd Tagged Copper Catalysts for the Synthesis of 1,4‐Disubstituted 1,2,3‐Triazoles and 5‐Substituted 1H‐Tetrazoles in Aqueous Medium
Abstract
ABSTRACT In this study, novel Mes‐Imd‐tagged copper catalysts, namely [MIMM] [Cu (OAc) 3 ], [BIMM] [Cu (OAc) 3 ] 2 , and [TIMM] [Cu (OAc) 3 ] 3 , were designed, synthesized, and characterized by different techniques. Their surfactant property was studied by conductometry and UV–Visible spectroscopy. These Mes‐Imd‐tagged copper catalysts were employed as “click catalysts” for the synthesis of a library of 1,4‐disubstituted triazoles and also applied for synthesis of mono‐substituted 1H‐tetrazoles with high yields in water. The scope and catalytic activity of these catalysts are described here for the first time. The benefit of this approach is that it can be recycled at least five times, use an aqueous medium, and worked at ambient temperature.
Fields of Study & Subjects
Click Chemistry and Applications
Synthesis of Tetrazole Derivatives
Multicomponent Synthesis of Heterocycles
Publication details
- Journal / source
- Applied Organometallic Chemistry
- Publisher
- Wiley
- Volume
- 40
- Issue
- 6
- Publication date
- 19 May 2026
- Language
- EN