Copper‐Catalyzed Asymmetric Hydroboration of Cyclic Dienes
Abstract
A copper-catalyzed enantioselective hydroboration of cyclic dienes, which afford enantioenriched allylboronates, is disclosed. This reaction is catalyzed by a chiral bisphosphine-Cu complex in combination with commercially available pinacolborane as the hydroborane source. The method is applicable to 1-aryl-cyclohexadienes and 1,2-dihydropyridine derivatives, affording allylboronate products in high regio- and enantioselectivity. The obtained allylboronates serve as versatile intermediates for the synthesis of diverse chiral compounds.
Fields of Study & Subjects
Organoboron and organosilicon chemistry
Asymmetric Hydrogenation and Catalysis
Catalytic C–H Functionalization Methods
Publication details
- Journal / source
- Chemistry - An Asian Journal
- Publisher
- Wiley
- Volume
- 21
- Issue
- 1
- Pages
- e70555–e70555
- Publication date
- 1 January 2026
- Language
- EN