Bioresorbable Electrically‐Active Neuromodulation Materials & Devices

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Authors: Jiajun Cheng, H. Li, Yao Chen, Liping Lin, Xinyue Zhang, Shuo Zhao, Qi An, Kaikai Guo, Zeguo Feng
Cited by: 1
References: 114

Abstract

Bioresorbable electrically-active neuromodulation devices (BEANDs) integrate degradable materials with the neuromodulation function of electrical stimulation, allowing the implants to gradually resorb after completing their therapeutic tasks and thereby eliminating the need for secondary removal surgery. This technological paradigm creates new opportunities for the treatment of neurological disorders. This review summarizes the material foundations of BEANDs, including the degradation pathways and biological effects of metals, natural polymers, and synthetic polymers; functional material systems comprising conductors, semiconductors, and dielectrics; and the core device modules required for operation, such as energy harvesting, storage, transmission, and regulation. We highlight the balance between material performance and bioresorbability and emphasize that multimodal energy management plays a critical role in achieving precise and personalized neuromodulation. Finally, we outline future directions in interdisciplinary integration and clinical translation, which are expected to advance BEANDs from proof-of-concept demonstrations toward practical clinical applications.

Fields of Study & Subjects

Neuroscience and Neural Engineering Planarian Biology and Electrostimulation Advanced Sensor and Energy Harvesting Materials

Publication details

Journal / source
Chemistry - An Asian Journal
Publisher
Wiley
Volume
21
Issue
2
Pages
e70565–e70565
Publication date
1 January 2026
Language
EN