Treatment outcomes of multidisciplinary management of recurrent urinary tract infections: A 2‐year experience in a dedicated complex‐UTI clinic

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Authors: Pragnitha Chitteti, I Ekpeno, Ahmed Ghonaimy, J Morris-Laverick, Stephanie Bezemer, Igor Kubelka, V McCune, Mehwash Nadeem
Cited by: 0
References: 25

Abstract

Objectives: This work aimed to assess treatment outcomes in patients with recurrent urinary tract infections (rUTIs) managed in a dedicated multidisciplinary complex-UTI clinic. In addition, this work aimed to evaluate the impact of tailored interventions on patient-reported outcomes, including quality of life (QoL) and symptomatic improvement. Materials and Methods: A 2-year, single-centre, prospective observational cohort study was conducted in a dedicated tertiary care UTI clinic. A multidisciplinary team comprising urologists, microbiologists and specialist nurses developed individualized management plans based on thorough assessments, including patient history, physical examination and necessary investigations. Data variables included patient demographics, urine culture results with antibiotic sensitivities, investigations performed and the treatment options administered. The minimum follow-up period was 6 months after the implementation of treatment in the clinic. Pretreatment and posttreatment QoL were assessed, along with posttreatment Patient Global Impression of Improvement (PGI-I) scores. Results: A total of 211 patients (mean age: 58.3 years, 89.6% female) were included. First- and second-line treatments were effective for 71% of patients, while 29% required tertiary interventions. Post-treatment, 81% of patients reported good-to-excellent improvement on the PGI-I scale, and 70% achieved good-to-excellent QoL. Overall treatment success, defined as reduced UTI frequency or symptom resolution, was reported in 87.7% of patients. Factors such as immunosuppression and history of hospital admission for urosepsis were associated with poor treatment outcomes with statistical significance. Conclusion: Dedicated multidisciplinary UTI clinics significantly improve treatment outcomes and QoL for patients with rUTIs. The findings support broader adoption of multidisciplinary approaches, emphasizing early intervention and tailored care to optimize clinical efficiency and enhance the patient experience.

Fields of Study & Subjects

Urinary Tract Infections Management Pediatric Urology and Nephrology Studies Urinary Bladder and Prostate Research

Publication details

Journal / source
BJUI Compass
Volume
7
Issue
3
Pages
e70177–e70177
Publication date
1 March 2026
Language
EN