Response to commentary on sequential nephron blockade vs . renin‐angiotensin system blockade in resistant hypertension: Methodological and safety clarifications

British Journal of Clinical Pharmacology 2026 Open access

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Authors: Juan Carlos Yugar‐Toledo, Tatiana Palotta Minari, Priscilla Galisteu de Mello, Elizabeth do Espírito Santo Cestário, Tatiane de Azevedo Rubio, Larissa Morete Caieiro da Costa, Louise Buonalumi Tácito Yugar, Luis Gustavo Sedenho‐Prado, Lúcia Helena Bonalume Tácito, Luciana Neves Cosenso‐Martin, André Fattori, Luciana Pellegrini Pisani
+2 more José Fernando Vilela-Martin, Heitor Moreno
DOI: 10.1002/bcp.70481
Cited by: 0
References: 6

Abstract

Critical Appraisal of the Yugar-Toledo et al.Study on Resistant Hypertension-Practical, Safety, Methodological, and Ethical Concerns'. 1 Constructive scientific dialogue is fundamental for the advancement of clinical knowledge, and we appreciate the opportunity to clarify methodological and safety aspects of our study.Below, we respond point by point to the comments regarding our article, 'Effects of different antihypertensive drug classes on central and ambulatory blood pressure in resistant hypertension: A randomized clinical trial', published in the British Journal of Clinical Pharmacology (BJCP). 2

Fields of Study & Subjects

Blood Pressure and Hypertension Studies Renin-Angiotensin System Studies Hormonal Regulation and Hypertension

Publication details

Journal / source
British Journal of Clinical Pharmacology
Volume
92
Issue
5
Pages
1519–1524
Publication date
8 February 2026
Language
EN