Multimodal MRI Reveals Brain Structural Differences and Executive Dysfunction in Early Methamphetamine Abstinence

Brain and Behavior 2026 Open access

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Authors: Ben Bristow, Maryam Tayebi, Paul Condron, Taylor Emsden, Tuta Ngārimu, Eryn E. Kwon, Rachael McLanachan, Gordon Liu, William S. Schierding, Patrick McHugh, Samantha Jane Holdsworth, Wendy Mohi
+2 more Gil Newburn, Miriam Scadeng
DOI: 10.1002/brb3.71288
Cited by: 0
References: 89

Abstract

BACKGROUND: Methamphetamine use disorder (MUD) is known to have profound effects on brain structure and cognitive functions. Understanding the extent of these neurobiological changes during the early abstinence period is crucial for developing targeted rehabilitation strategies. OBJECTIVE: This study aimed to investigate structural brain alterations and cognitive functions in early abstinent methamphetamine users compared with healthy controls. METHODS: A total of 27 participants were included, comprising 13 participants with MUD in early abstinence (

Fields of Study & Subjects

Functional Brain Connectivity Studies

Publication details

Journal / source
Brain and Behavior
Volume
16
Issue
5
Pages
e71288–e71288
Publication date
1 May 2026
Language
EN