Cervical Intranodal Schwannoma and Its Malignant Transformation: A Case Report With Literature Review

Clinical Case Reports 2026 Open access

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Authors: Shahab Hussain, Zia Ullah Khan, Nazneen Liaqat, Syed Wajihullah Shah, Kainat Khan, Jibran Ikram
DOI: 10.1002/ccr3.71801
Cited by: 0
References: 19

Abstract

This case report highlights a rare malignant transformation of a cervical intranodal schwannoma in a 46-year-old man. The patient first came in with a slow-growing, painless nodule in the right neck. Surgical excision was performed and histopathological examinations revealed a benign intranodal cellular schwannoma. Eighteen months later, the mass recurred and a second surgery showed malignant peripheral nerve sheath tumor (MPNST) at the same site, confirming malignant transformation. This case adds to the limited knowledge of this rare event.

Fields of Study & Subjects

Neurofibromatosis and Schwannoma Cases Facial Nerve Paralysis Treatment and Research Meningioma and schwannoma management

Publication details

Journal / source
Clinical Case Reports
Volume
14
Issue
1
Pages
e71801–e71801
Publication date
1 January 2026
Language
EN