Stroke‐Like Migraine Attacks After Radiation Therapy ( SMART ) Syndrome: A Case Report and Review of a Rare Delayed Complication of Cranial Irradiation

Clinical Case Reports 2026 Open access

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Authors: Shiv Jha, Yugant Khand, Surabhi Ranjan, Monika Pandit, Eric Mariuma
DOI: 10.1002/ccr3.71952
Cited by: 0
References: 9

Abstract

SMART syndrome is a rare, delayed complication of cranial irradiation that can mimic stroke, tumor recurrence, or autoimmune encephalitis. Early recognition based on clinical-radiologic features is critical to avoid misdiagnosis and unnecessary interventions since conservative management often leads to complete recovery.

Fields of Study & Subjects

Brain Metastases and Treatment Neurological Complications and Syndromes Effects of Radiation Exposure

Publication details

Journal / source
Clinical Case Reports
Volume
14
Issue
2
Pages
e71952–e71952
Publication date
28 January 2026
Language
EN