Successful Pregnancies Following Liver Transplantation for Wilson's Disease: A Case Report and Literature Review

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Authors: Harutyunyan Hayk, Homeira Vafaei, Voskanyan Arayik, Barseghyan Hayrapet, Saman Nikeghbalian, Atefe Hashemi, Hamide Barzegar
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References: 27

Abstract

Pregnancy in women with a history of liver transplantation is considered high risk due to concerns about graft function, immunosuppressive therapy, and maternal-fetal complications. We present the case of a young woman who underwent liver transplantation for fulminant hepatic failure in adolescence and subsequently achieved two successful pregnancies with favorable maternal and neonatal outcomes. Her pregnancies were carefully managed through close collaboration between transplant specialists and obstetricians, with regular monitoring of graft function, immunosuppressive levels, and maternal-fetal well-being. Both deliveries were uneventful, and long-term follow-up revealed stable graft function and healthy children. A review of previously reported cases demonstrates that while risks such as preterm delivery, low birth weight, and hypertensive disorders exist, favorable outcomes are increasingly achievable with meticulous multidisciplinary care. This case highlights the potential for successful pregnancies following liver transplantation and emphasizes the importance of individualized management, patient counseling, and long-term follow-up.

Fields of Study & Subjects

Organ Transplantation Techniques and Outcomes Cardiovascular Issues in Pregnancy Pregnancy and Medication Impact

Publication details

Journal / source
Clinical Case Reports
Volume
14
Issue
2
Pages
e72022–e72022
Publication date
1 February 2026
Language
EN