Leukocyte Chemotactic Factor 2 Amyloidosis ( LECT ‐2) Amyloidosis Case Report and Review of the Current Literature

Clinical Case Reports 2026 Open access

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Authors: Ahmad Samir Matarneh, Bayan Matarneh, Omar Khaleel Mohammad Salameh, Sundus Sardar, Catherine S. Abendroth, Nasrollah Ghahramani, Navin Kumar Verma
DOI: 10.1002/ccr3.72055
Cited by: 1
References: 14

Abstract

Amyloid deposition is an increasingly recognized contributor to chronic kidney disease and end-stage renal disease. It can result from various underlying conditions, including monoclonal gammopathies and chronic inflammatory states. Diagnosis is typically established by kidney biopsy demonstrating characteristic amyloid deposits. ALECT2 (leukocyte chemotactic factor 2) amyloidosis can present as nephrotic-range proteinuria. ALECT2 amyloidosis is an uncommon and under-recognized.

Fields of Study & Subjects

Amyloidosis: Diagnosis Treatment Outcomes Dialysis and Renal Disease Management Parathyroid Disorders and Treatments

Publication details

Journal / source
Clinical Case Reports
Publisher
Wiley
Volume
14
Issue
2
Pages
e72055–e72055
Publication date
1 February 2026
Language
EN