Trimethoprim/Sulfamethoxazole‐Induced Systemic Toxic Epidermal Necrolysis Syndrome: A Case Report

Clinical Case Reports 2026 Open access

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Authors: Qing Wang, Litong Chen, Wen Ye
DOI: 10.1002/ccr3.72512
Cited by: 1
References: 11

Abstract

Trimethoprim/sulfamethoxazole can induce life-threatening toxic epidermal necrolysis. Early recognition, immediate drug cessation, and multidisciplinary supportive care are critical. Even with aggressive therapy, mortality remains high, and SCORTEN score aids in prognostication.

Fields of Study & Subjects

Drug-Induced Adverse Reactions Pneumocystis jirovecii pneumonia detection and treatment Pharmacovigilance and Adverse Drug Reactions

Publication details

Journal / source
Clinical Case Reports
Publisher
Wiley
Volume
14
Issue
5
Pages
e72512–e72512
Publication date
23 April 2026
Language
EN