Rare Manifestation of Sjogren's Syndrome: Renal Tubular Acidosis‐Induced Hypokalemic Paralysis—A Case Report
Abstract
Sjogren's syndrome (SS) is an autoimmune disorder characterized by inflammation of exocrine glands, often presenting with symptoms such as dry eyes and mouth. Although less common, renal involvement can lead to serious complications like hypokalemic paralysis. We report a case of a 28-year-old female with no prior medical history, who initially presented with fever, myalgia, and arthralgia. Her condition later progressed to hypokalemia and metabolic acidosis. Further evaluation confirmed Type 1 renal tubular acidosis (RTA) secondary to SS. Treatment with potassium supplementation, steroids, and bicarbonate resolved the symptoms. This case highlights the importance of considering renal involvement in SS patients and underscores the need for prompt intervention to prevent severe complications.
Fields of Study & Subjects
Salivary Gland Disorders and Functions
Coagulation
Bradykinin
Polyphosphates
and Angioedema
Thyroid and Parathyroid Surgery
Publication details
- Journal / source
- Clinical Case Reports
- Volume
- 14
- Issue
- 5
- Pages
- e72655–e72655
- Publication date
- 1 May 2026
- Language
- EN