Retroperitoneal Extra‐Adrenal Paraganglioma Presenting With Secondary Amenorrhea and Hypertension in an Adolescent: A Rare Case From Sub‐Saharan Africa
Abstract
Extra-adrenal paragangliomas are rare neuroendocrine tumors that may cause hypertension and reproductive dysfunction in adolescents. We report a 16-year-old girl with uncontrolled hypertension and secondary amenorrhea caused by a functional Organ of Zuckerkandl paraganglioma. Surgical excision restored normal blood pressure and menstruation, highlighting reversible catecholamine-induced hypothalamic-pituitary-gonadal axis suppression.
Fields of Study & Subjects
Adrenal and Paraganglionic Tumors
Hormonal Regulation and Hypertension
Neuroblastoma Research and Treatments
Publication details
- Journal / source
- Clinical Case Reports
- Volume
- 14
- Issue
- 7
- Pages
- e73034–e73034
- Publication date
- 22 June 2026
- Language
- EN