Case Series of Intracranial Central Primitive Neuroectodermal Tumor in Two Adults Treated With Craniospinal Irradiation

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Authors: Shubham Dokania, Sambit Nanda S, Ipsita Dhal, Ajay Choubey K, Ninad Patil H, Jhansi Pattanaik, Pritam Mondal, Ashutosh Mukherji
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References: 11

Abstract

ABSTRACT Ewing sarcoma and primitive neuroectodermal tumors share histological and genetic characteristics, yet differ in management, with EWSR1 rearrangement being the key distinguishing factor. Such intracranial tumors lacking this rearrangement are rare in adults. This series highlights the diagnostic challenge and poor outcomes despite standard treatment.

Fields of Study & Subjects

Sarcoma Diagnosis and Treatment Glioma Diagnosis and Treatment Management of metastatic bone disease

Publication details

Journal / source
Clinical Case Reports
Volume
14
Issue
7
Pages
e73093–e73093
Publication date
1 July 2026
Language
EN