Case Series of Intracranial Central Primitive Neuroectodermal Tumor in Two Adults Treated With Craniospinal Irradiation
Abstract
ABSTRACT Ewing sarcoma and primitive neuroectodermal tumors share histological and genetic characteristics, yet differ in management, with EWSR1 rearrangement being the key distinguishing factor. Such intracranial tumors lacking this rearrangement are rare in adults. This series highlights the diagnostic challenge and poor outcomes despite standard treatment.
Fields of Study & Subjects
Sarcoma Diagnosis and Treatment
Glioma Diagnosis and Treatment
Management of metastatic bone disease
Publication details
- Journal / source
- Clinical Case Reports
- Volume
- 14
- Issue
- 7
- Pages
- e73093–e73093
- Publication date
- 1 July 2026
- Language
- EN