Incidental Mandibular FDG Uptake on PET / CT Preceding Medication‐Related Osteonecrosis of the Jaw in a Patient Receiving High‐Dose Denosumab: A Case Report

Clinical Case Reports 2026 Open access

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Authors: Yuki Sakamoto, Shunsuke Sawada, Masahiro Umeda, Yuka Kojima
DOI: 10.1002/ccr3.73185
Cited by: 1
References: 5

Abstract

In a 59-year-old edentulous woman on high-dose denosumab, incidental mandibular FDG uptake (SUVmax: 5.1) on PET/CT preceded Stage 2 MRONJ by 12 months, despite normal conventional imaging. This suggests that PET/CT may help detect early, subclinical MRONJ development.

Fields of Study & Subjects

Bone health and treatments Oral health in cancer treatment Head and Neck Cancer Studies

Publication details

Journal / source
Clinical Case Reports
Publisher
Wiley
Volume
14
Issue
7
Pages
e73185–e73185
Publication date
1 July 2026
Language
EN