A Masked Low‐Coordinate and Polarized Au(I)/Pt(0) Complex for Cooperative CX and CH Bond Activation of Pyridines

ChemistryEurope 2026 Open access

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Authors: Martina Landrini, Jefferson Guzmán, Nereida Hidalgo, Miguel Ángel Gaona, Juan José Moreno, Jesús Campos
DOI: 10.1002/ceur.202500376
Cited by: 1
References: 83

Abstract

Bulky terphenyl phosphine ligands allow the isolation of a masked low‐coordinate, highly polarized Au(I)/Pt(0) complex. At variance to the inertness of prior coordinatively saturated AuPt systems, this complex exhibits cooperative reactivity toward pyridines. CX activation is observed for 2‐halopyridines (X = I, Br, Cl), while selective ortho ‐CH activation of pyridine‐ N ‐oxide yields an unexpected pyridylidene carbene structure. Computational studies support the synergistic effect of the two metals during bond activation and shed light on the electronic structure of some of these unique species.

Fields of Study & Subjects

Catalytic C–H Functionalization Methods Catalytic Cross-Coupling Reactions Catalytic Alkyne Reactions

Publication details

Journal / source
ChemistryEurope
Publisher
Wiley
Volume
4
Issue
1
Publication date
1 January 2026
Language
EN