Cover Picture

Although asymmetric catalytic synthesis via dynamic kinetic resolution has proven to serve as a powerful tool for the efficient preparation of planar chiral pillar[5]arenes, the enantioselective synthesis of highly‐functionalized pillar[5]arenes with more than two functional groups remains rarely explored. Herein, by successfully developing catalytically four‐fold asymmetric Sonogashira coupling, we have realized the enantioselective synthesis of diverse tetra‐functionalized planar chiral pillar[5]arenes, not only enriching the synthetic methods for planar chiral pillararenes with high functionalization degree, but also giving access to diverse promising chiral building blocks for practical applications. More details are discussed in the article by Wang et al . on pages 335—342. image