From channel‐spatial attention to state space models: A review of evolving mechanisms in tumour segmentation

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Authors: Yanfei Sun, Yi-Xiang Wang, Rui Yin
Cited by: 2
References: 59

Abstract

Abstract Objective This review delineates the evolution of attention architectures in automated tumor segmentation across three pivotal paradigms: classic Pre‐Transformer attention, dominant Transformer‐based self‐attention, and emerging Mamba‐based state space models. Methods We synthesize their functional roles—from channel enhancement to long‐range dependency modelingand critically assess hybrid structures designed for multimodal clinical oncology scenarios. Findings/Results The review establishes attention mechanisms as a foundational pillar for the next generation of intelligent segmentation tools, highlighting their potential in feature enhancement and localization. Conclusion Interrogating current challenges and charting future trajectories, these mechanisms are poised to profoundly impact the landscape of precision medicine.

Fields of Study & Subjects

Advanced Neural Network Applications AI in cancer detection Generative Adversarial Networks and Image Synthesis

Publication details

Journal / source
Clinical and Translational Discovery
Publisher
Wiley
Volume
6
Issue
2
Publication date
26 February 2026
Language
EN