Salivary Duct Carcinoma: Report of an Advanced Challenging Case Diagnosed by Ultrasound‐Guided Fine‐Needle Aspiration Biopsy
Abstract
We report a rare case of salivary duct carcinoma (SDC) in a 67-year-old male who presented with a rapidly enlarging, ill-defined left upper neck mass, accompanied by both cervical and axillary lymphadenopathy. Initial punch biopsy of the neck mass suggested metastatic breast carcinoma. However, ultrasound-guided fine-needle aspiration (US-FNA) and comprehensive immunohistochemical analysis, in conjunction with radiologic findings, confirmed the diagnosis of SDC. This case highlights the diagnostic challenges of SDC and reinforces the pivotal role of US-FNA cytology in establishing a definitive diagnosis while minimizing invasive procedures.
Fields of Study & Subjects
Salivary Gland Tumors Diagnosis and Treatment
Head and Neck Cancer Studies
Ear and Head Tumors
Publication details
- Journal / source
- Diagnostic Cytopathology
- Publisher
- Wiley
- Volume
- 54
- Issue
- 5
- Pages
- E131–E135
- Publication date
- 2 February 2026
- Language
- EN