A Photoredox Radical‐Polar Crossover Reaction for the Preparation of Monoprotected Dicarbonyl Compounds
Abstract
An efficient, ATRA (Atom‐Transfer Radical Addition)‐based, Ru‐photocatalyzed radical‐polar crossover reaction for the preparation of monoprotected dicarbonyl compounds is reported. This procedure is based on the capture of a cationic intermediate, arising from the radical step, with diverse nucleophiles. Additionally, we have extended this methodology to the synthesis of 1,5‐dicarbonyl compounds by using cyanide as the oxocarbenium‐capturing nucleophile.
Fields of Study & Subjects
Radical Photochemical Reactions
Catalytic C–H Functionalization Methods
Catalytic Cross-Coupling Reactions
Publication details
- Journal / source
- European Journal of Organic Chemistry
- Volume
- 29
- Issue
- 6
- Publication date
- 10 January 2026
- Language
- EN