Photoinduced Silver(I)‐Mediated Direct Alkoxycarbonylation of Quinoxalin‐2(1 H )‐ones With Alkyloxalyl Chlorides

European Journal of Organic Chemistry 2026

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Authors: Yunzheng Zhou, Shi‐Ya He, Wu Liang, Fang Liu, Xin‐Ran Sun, Shao‐Qun Cai, Zhi Yang, Jun‐Fei Zhao, Shi‐Cui Fang, Bin Pan, Fei Du
DOI: 10.1002/ejoc.202501140
Cited by: 1
References: 56

Abstract

A silver‐ and light‐mediated radical alkoxycarbonylation of quinoxalin‐2(1 H )‐ones has been developed. This direct esterification protocol provides efficient access to quinoxaline‐3‐carboxylates. The operationally simple reaction features good functional group compatibility, and mild conditions. Notably, the successful late‐stage functionalization of complex molecules demonstrates significant synthetic utility for modifying biologically active natural products.

Fields of Study & Subjects

Radical Photochemical Reactions Catalytic C–H Functionalization Methods Cyclopropane Reaction Mechanisms

Publication details

Journal / source
European Journal of Organic Chemistry
Publisher
Wiley
Volume
29
Issue
8
Publication date
28 January 2026
Language
EN