Photochemical Amination of Thioethers Under Biphasic Flow Conditions
Abstract
A practical, continuous flow, biphasic photochemical amination of thioethers, employing N ‐mesyloxycarbamates as nitrene precursors, is reported. Using UVA irradiation at 365 nm and Fe(acac) 3 as a catalyst, the reaction efficiently converts aromatic and aliphatic thioethers into Troc‐protected sulfilimines in high yields. The biphasic ethyl acetate/water system plays a critical role in preventing clogging of the reactor by dissolving the mesylate byproduct.
Fields of Study & Subjects
Innovative Microfluidic and Catalytic Techniques Innovation
Synthesis and Catalytic Reactions
Radical Photochemical Reactions
Publication details
- Journal / source
- European Journal of Organic Chemistry
- Publisher
- Wiley
- Volume
- 29
- Issue
- 8
- Publication date
- 30 January 2026
- Language
- EN