Base‐Mediated C–C Bond Cleavage Toward 2‐(2‐ oxo ‐2‐Phenylethyl)‐2‐phenylindolin‐3‐ones

European Journal of Organic Chemistry 2026

View at publisher
Authors: Faxiu Feng, Wenjun Wang, Xiaoming Liao, Zhuoran Yang, Ping Li, Xiaoxiang Zhang
DOI: 10.1002/ejoc.202501196
Cited by: 1
References: 52

Abstract

A straightforward method for cleaving carbon–carbon bonds under metal‐free, base conditions was reported. Efficient synthesis of desired products with 2,3‐fused diaminoindoles scaffold is achieved by reacting 2,2‐disubstituted indolin‐3‐ones with thioureas, leveraging mild reaction conditions and a short reaction time as advantageous features of the method.

Fields of Study & Subjects

Catalytic C–H Functionalization Methods Synthesis and bioactivity of alkaloids Synthesis and Characterization of Pyrroles

Publication details

Journal / source
European Journal of Organic Chemistry
Publisher
Wiley
Volume
29
Issue
7
Publication date
24 January 2026
Language
EN