Kinship Inferences for Second‐Degree Relatives With a Combination of STRs and Microhaplotypes

Electrophoresis 2026 Open access

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Authors: Jiaming Xue, Qiushuo Wu, Mengyu Tan, Yazi Zheng, Guihong Liu, Haoyan Jiang, Yuxuan Tan, Yuanyuan Xiao, Meli Lv, Shengqiu Qu, W X Liang, Li Zhang
DOI: 10.1002/elps.70122
Cited by: 1
References: 31

Abstract

ABSTRACT This study evaluated kinship identification using 19 short tandem repeats (STRs) from AGCU EX22 kit, 119 microhaplotypes (52 in Panel A + 67 in Panel B), and a theoretical 9622 genome‐wide single nucleotide polymorphisms (SNPs) panel (The 9K). The system power was assessed accounting for linkage on the basis of 198 Chinese Southern Han (CHS) family samples and simulated data. STR + Panels A and B distinguished full‐sibling (FS) from unrelated (un), with second‐degree effectiveness above 0.96 when log 10 (LR) threshold was 4 and low false positive rate (

Fields of Study & Subjects

Forensic and Genetic Research Genetic Associations and Epidemiology Evolutionary Psychology and Human Behavior

Publication details

Journal / source
Electrophoresis
Publisher
Wiley
Volume
47
Issue
8
Pages
779–787
Publication date
2 July 2026
Language
EN