Honey as a Natural Flavorful Product: A Comprehensive Review of Its Potential Biological Activities and Recent Studies

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Authors: Ecem Bolat, Ahmet Alperen Canbolat, Sümeyye Sarıtaş, Mauro Lombardo, Anna Maria Witkowska, Hesham El‐Seedi, Mikhaël Bechelany, Sercan Karav
Cited by: 3
References: 312

Abstract

) with low water content. Its color ranges from white to amber, with taste varying accordingly. The chemical form and viscosity of honey depend on its composition. It mainly contains sugars and water, along with proteins, enzymes, polyphenols, vitamins, and minerals. Used for centuries as both food and medicine, honey also serves in alternative treatments. Its bioactive molecules such as phenolics, flavonoids, and enzymes exhibit antimicrobial, antioxidant, anti-inflammatory, anticancer, and antidiabetic properties. Moreover, it offers cardio- and neuroprotective benefits, reinforcing its medicinal value. Honey promotes wound healing, infection prevention, and tissue regeneration. Its antimicrobial activity, primarily driven by hydrogen peroxide and phytochemicals, is effective against wound and burn infections. It may also relieve asthma, support digestion, and help prevent cancer. Recent studies have highlighted honey's involvement in key bioactive mechanisms, including modulation of oxidative stress, regulation of inflammatory pathways, and enhancement of cellular repair processes. Varieties such as Manuka, Tualang, and Sidr show distinct therapeutic effects depending on their botanical and geographical origins. Understanding their composition is key for developing targeted therapeutic applications. This review explores honey's composition and therapeutic potential, emphasizing its rich bioactive profile, which continues to attract scientific interest for treating various health conditions and promoting overall well-being.

Fields of Study & Subjects

Bee Products Chemical Analysis Healthcare and Venom Research Microencapsulation and Drying Processes

Publication details

Journal / source
Food Science & Nutrition
Publisher
Wiley
Volume
14
Issue
4
Pages
e71645–e71645
Publication date
1 April 2026
Language
EN