Implementation of Large‐Scale Multi‐Reactor Automation for Process Development
Abstract
ABSTRACT Pharmaceuticals increasing complexity requires longer synthesis with unique processes for each step, increasing the number of experiments to develop robust sustainable processes. The time to develop these processes is getting shorter, and automation can support the growing need to efficiently perform more experiments. Automation reaction screening focuses more on small‐scale high‐throughput experimentation (HTE), which may not be applicable for late phase process development. To support these activities and decrease development time, we describe the implementation of a flexible large‐scale multi‐reactor automation platform for process development.
Fields of Study & Subjects
Innovative Microfluidic and Catalytic Techniques Innovation
Process Optimization and Integration
Chemistry and Chemical Engineering
Publication details
- Journal / source
- Helvetica Chimica Acta
- Publisher
- Wiley
- Volume
- 109
- Issue
- 3
- Publication date
- 10 January 2026
- Language
- EN