Ultra‐Processed Food Consumption, Mental Health, and Quality of Life in Adults: A Systematic Review Protocol

Background and Aims: The consumption of ultra-processed foods is linked to an increase in chronic noncommunicable diseases and risk of mortality. Adverse effects on health have a direct impact on quality of life, compromising general well-being. Thus, with this systematic review protocol, we aimed to review the literature on the association of high consumption of ultra-processed foods with quality of life and mental health in adults and quantify it through meta-analysis. Methods: This protocol is based on PRISMA-P and has been registered on PROSPERO (CRD42024599909). The CINAHL, EMBASE, FSTA, LILACS, Scopus, Ovid, PsycNET, PubMed, and Web of Science databases will be searched. This strategy uses the MeSH terms and their variations. The search was limited to original peer-reviewed articles with no language restrictions. Two reviewers independently read and extracted data. Methodological quality and risk of bias will be assessed using the GRADE, CASP, and Downs and Black methods. Results: This protocol describes how the results of the systematic review will be organized, detailing the procedures for study selection, inclusion, and data analysis. Conclusions: PROSPERO: CRD42024599909.