Hypertensive retinopathy in pre‐eclampsia and its association with disease severity and neonatal outcomes: A retrospective cohort study

International Journal of Gynecology & Obstetrics 2026 Open access

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Authors: G. Saccone, Francesco Matarazzo, Mariarosaria Motta, Marika Ylenia Rovetto, M M Rinaldi, Maurizio Guida, C Costagliola
DOI: 10.1002/ijgo.70818
Cited by: 1
References: 15

Abstract

INTRODUCTION: Pre-eclampsia (PE) involves systemic endothelial dysfunction and microvascular injury, yet routine obstetric care lacks noninvasive readouts of maternal microvascular health. We evaluated whether hypertensive retinopathy (HR) detected during pregnancy is associated with maternal disease severity and adverse neonatal outcomes. METHODS: We performed a retrospective cohort study of singleton pregnancies with PE and at least one ophthalmic assessment during pregnancy. Retinal findings were graded as none, mild, moderate, or severe. Primary outcomes were maternal composite adverse outcome (severe features, HELLP syndrome, eclampsia, admission to intensive care unit) and neonatal composite adverse outcome (indicated delivery

Fields of Study & Subjects

Pregnancy and preeclampsia studies Neurological Complications and Syndromes Retinopathy of Prematurity Studies

Publication details

Journal / source
International Journal of Gynecology & Obstetrics
Publisher
Wiley
Volume
174
Issue
1
Pages
229–234
Publication date
22 January 2026
Language
EN