Acute kidney injury, secondary to valacyclovir use during pregnancy for the prevention of fetal cytomegalovirus infection
Abstract
High dose valacyclovir treatment of pregnant women has become a common treatment for primary CMV infection, to prevent vertical transmission to the fetus. We present a case of a healthy young pregnant female with primary CMV infection during the first trimester who was diagnosed with acute kidney injury secondary to valacyclovir treatment. This case serves as a reminder to clinicians that prescription of high dose valacyclovir, to prevent vertical transmission of CMV to the fetus, carries a risk of approximately 1% of AKI.
Fields of Study & Subjects
Cytomegalovirus and herpesvirus research
Pregnancy and Medication Impact
Parvovirus B19 Infection Studies
Publication details
- Journal / source
- International Journal of Gynecology & Obstetrics
- Publisher
- Wiley
- Volume
- 175
- Issue
- 1
- Pages
- 493-494
- Publication date
- 18 April 2026
- Language
- EN