RNA viral protein structure database: A comprehensive and user‐friendly web database for RNA viral protein structures

iMetaOmics. 2026 Open access

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Authors: Qiangzhen Yang, Zhongshuai Tian, Tao Hu, Jiangrong Lou, Hengcong Liu, Edward C Holmes, Yongyong Shi, Juan Li, Weifeng Shi
DOI: 10.1002/imo2.70120
Cited by: 1
References: 20

Abstract

Given the central role of protein structures in RNA virus biology, the RNA viral protein structure database (RVPSD, https://virus.9itsg.net) integrates taxonomic classification, viral nucleotide and protein sequences, functional annotations, and predicted three-dimensional protein structures. Currently, RVPSD comprises 154,716 AlphaFold2-predicted RNA viral protein structures from 5263 RNA virus species, with > 80% exhibiting high predicted local distance difference test scores. RVPSD also provides a searchable and interactive web interface to support comparative structural analyses and functional annotation of viral dark matter.

Fields of Study & Subjects

RNA and protein synthesis mechanisms Machine Learning in Bioinformatics Bacteriophages and microbial interactions

Publication details

Journal / source
iMetaOmics.
Publisher
Wiley
Volume
3
Issue
3
Publication date
13 July 2026
Language
EN