Synthesis of Dibenzo‐1,2,3‐Triazole Fused 14‐Membered Oxa‐Ketone Macrocycles via Azide‐Alkyne Cycloaddition

Journal of Heterocyclic Chemistry 2026

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Authors: Nasrin Jahan, Eman Ali SK, Arijit Das, Rajlakshmi Laha, Somasri Dam, Inul Ansary
DOI: 10.1002/jhet.70180
Cited by: 0
References: 42

Abstract

ABSTRACT We have successfully synthesized for the first time a series of dibenzo‐1,2,3‐triazole fused 14‐membered oxa‐ketone macrocycles 9a‐j in (61%–92%) yields, from cross‐aldol precursors (1 E ,4 E )‐1‐(2‐azidophenyl)‐5‐(alkyl‐2/6‐(prop‐2‐yn‐1‐yloxy)aryl)penta‐1,4‐dien‐3‐ones 8a‐j , by employing Cu(I)/Ag(I)‐ catalyzed azide‐alkyne cycloaddition reactions.

Fields of Study & Subjects

Click Chemistry and Applications Supramolecular Chemistry and Complexes Organic Chemistry Cycloaddition Reactions

Publication details

Journal / source
Journal of Heterocyclic Chemistry
Volume
63
Issue
5
Pages
905–912
Publication date
4 March 2026
Language
EN