Cardiac Resynchronization Therapy: Reconsidering Its Essence as a Treatment for Electrical Dyssynchrony in Heart Failure
Abstract
Cardiac resynchronization therapy (CRT) essentially targets electrical dyssynchrony, one of the key drivers in heart failure (HF). Its efficacy depends on both the quality (QRS morphology) and quantity (QRS duration) of dyssynchrony, requiring individualized patient selection. While drug therapy for HF has a limited effect on this substrate, early implantation of CRT can prevent irreversible remodeling and facilitate optimization of medical therapy. CRT should be recognized as an essential component within a comprehensive strategy for HF management in patients with appropriate indications.
Fields of Study & Subjects
Cardiac pacing and defibrillation studies
ECG Monitoring and Analysis
Heart Failure Treatment and Management
Publication details
- Journal / source
- Journal of Arrhythmia
- Volume
- 42
- Issue
- 1
- Pages
- e70268–e70268
- Publication date
- 9 January 2026
- Language
- EN