Wild Type Transthyretin Amyloid Cardiomyopathy Hidden Under Ablation‐Refractory Atrial Arrhythmias and the Potential Contribution of Tafamidis in Rhythm Control

Journal of Arrhythmia 2026 Open access

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Authors: Tomoki Horie, Yasutoshi Nagata, Toshihiro Nozato, Shinsuke Miyazaki, Takashi Ashikaga
DOI: 10.1002/joa3.70271
Cited by: 0
References: 4

Abstract

An octogenarian man with a history of multiple catheter ablation failures for atrial fibrillation and tachycardia was diagnosed with transthyretin amyloid cardiomyopathy. After 1 year of tafamidis therapy, the patient experienced spontaneous restoration of sinus rhythm, and follow-up image of 99mTc-pyrophosphate scintigraphy revealed a marked decrease of tracer accumulation.

Fields of Study & Subjects

Amyloidosis: Diagnosis Treatment Outcomes Cardiac electrophysiology and arrhythmias Atrial Fibrillation Management and Outcomes

Publication details

Journal / source
Journal of Arrhythmia
Volume
42
Issue
1
Pages
e70271–e70271
Publication date
13 January 2026
Language
EN